Monday, 19 March 2012

PDB & Rasmol


Today, we learned about Protein Data Bank, or in its short form, we call it as PDB. The Protein Data Bank is a repository for the 3-D structural data of large biological molecules, such as proteins and nucleic acis. Typically, the data are obtained by X-ray crystallography or NMR spectroscopy and submittted by biochemists and biologist from around the world. Besides, they are freely accessible on the Internet via the websites of its member organisations, for instance, PDBe, PDBj and RCSB. In addition, PDB is a key resource in areas of structural biology, such as structural genomics. For most major scientific journals, and some funding agencies, such as the NIH in the USA, now need scientists to submit their data to the PDB.

After learning about PDB, we are asked to do some assignment about this topic. In this assignment, we need to collect the information of the molecular gained from the website: http://www.pdb.org/pdb/home/home.do 

Apart from that, we have to edit some of the molecular, such as Collagenase, Subtilisin, Kexin and Signal Peptidase. Therefore, below is the information about each of them.





 Molecule nameCOLLAGENASE
 ClassificationHYDROLASE 
 Brookhaven code2Y72
 Number of chains4
 Structure weight 17893.70
 Length 85
 Polymer1






 Molecule nameKEXIN
 ClassificationHYDROLASE/HYDROLASE INHIBITOR
 Brookhaven code2ID4
 Number of chains2
 Structure weight113264.63
 Length 503
 Polymer1






 Molecule nameCHYMOTRYPSIN INHIBITOR 2
 ClassificationSERINE PROTEASE INHIBITOR
 Brookhaven code1CIQ
 Number of chains1
 Structure weight 7331.70
 Length 40
 Polymer1






 Molecule namePROTEASE 4
 ClassificationHYDROLASE 
 Brookhaven code3BEZ
 Number of chains4
 Structure weight 258495.20
 Length593
 Polymer1





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